Failed Back Surgery Syndrome (FBSS) is a term used to describe persistent or worsening pain following spinal surgery. Studies suggest that as many as 40% of patients experience ongoing pain after back surgery, with some requiring additional procedures that may not always provide relief. Whether caused by scar tissue formation, nerve damage, or improper spinal fusion, FBSS can lead to chronic discomfort, reduced mobility, and frustration for patients seeking relief.
At OrthoGen Health, we offer non-surgical regenerative medicine solutions designed to address the root causes of failed back surgery pain, reduce inflammation, and promote spinal tissue repair. Using platelet-rich plasma (PRP), exosome therapy, and stem cell treatments, our approach helps patients regain function and avoid the risks associated with repeat surgeries.
“Someone referred me to this place because i had a very bad knee pain which multiple other doctors i visited, told me have to have an open surgery but Dr.James told me can do PRP which is much easier and safer. I thought it worth trying it. After almost 2 years, i still have no pain and i got back to normal life. I am so glad listen to Dr, James and for your info i think he has one of the highest certificates that only a few doctors in the US have it.
He is so kind and acknowledgeable and i definitely recommend anyone who has joint pain before letting others to have any open surgeries which obviously they want nothing but making money.Thanks you for making the life enjoyable for me again.”
Why Does Back Surgery Fail?
Although spinal surgery is intended to correct structural problems, there are several reasons why pain may persist or return after a procedure:
Scar Tissue Formation
Post-surgical scar tissue can compress nerves and lead to chronic pain.
Nerve Damage
Surgery can inadvertently cause nerve irritation or incomplete nerve healing.
Incomplete Spinal Fusion
Some patients experience failed bone fusion, leading to instability and continued discomfort.
Adjacent Segment Disease
Spinal surgery may place added stress on nearby discs, causing degeneration in surrounding areas.
Misdiagnosis of Pain Source
If the original diagnosis was incorrect, surgery may not fully address the root cause of pain.
How Regenerative Medicine Supports Failed Back Surgery Recovery
Instead of relying on pain medications, nerve blocks, or revision surgeries, regenerative medicine provides a natural, long-term solution to FBSS pain. These therapies work by repairing damaged tissues, reducing inflammation, and enhancing nerve regeneration.
Platelet-Rich Plasma (PRP) Therapy
PRP is derived from the patient’s own blood and contains healing growth factors that reduce inflammation and promote tissue repair.
Exosome Therapy
Exosomes are cellular messengers that deliver regenerative signals to damaged spinal tissues, improving nerve function and reducing chronic pain.
Stem Cell Therapy
Stem cells assist in regenerating spinal discs, improving nerve healing, and restoring mobility.
Biologic Injections
These injections provide anti-inflammatory support and long-lasting pain relief by addressing the underlying causes of FBSS.
Research indicates that PRP and stem cell therapy can significantly reduce pain and improve function in patients with chronic spinal conditions, offering an alternative to repeat surgeries.
Frequently Asked Questions About Regenerative Therapy for Failed Back Surgery Syndrome
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Yes, PRP, exosome, and stem cell therapies target underlying inflammation, nerve damage, and scar tissue formation, providing relief even when previous surgeries were unsuccessful.
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Unlike revision surgery, regenerative treatments are minimally invasive, require little to no downtime, and promote the body’s natural healing processes without additional structural changes.
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Yes, PRP, stem cell, and exosome therapies use biologic materials derived from your own body or natural sources, reducing risks associated with surgery or long-term medication use.
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Many patients experience reduced pain and improved mobility within weeks, with continued progress over time as healing occurs at the cellular level.
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Yes, regenerative medicine supports nerve regeneration, reduces inflammation around compressed nerves, and promotes better spinal function for long-term pain relief.

Dr. James Petros
Dr. James Petros, founder of OrthoGen Health, is a board-certified regenerative medicine physician with extensive expertise in pain management and non-surgical orthopedics. Now serving primarily in his role as CEO, Dr. Petros focuses on advancing the mission of OrthoGen Health through innovation, clinical leadership, and patient-centered strategy. He has built the organization on a foundation of scientific progress, compassionate care, and collaboration, ensuring that patients are supported by a team dedicated to delivering the highest quality regenerative therapies.
Find Long-Term Back Pain Relief in San Jose
If you are experiencing lingering pain after spinal surgery, OrthoGen Health in San Jose and Los Gatos offers advanced regenerative medicine therapies to help you recover naturally and regain mobility.
Schedule a consultation today to explore your options for non-surgical failed back surgery recovery and long-term spine health.