Shingles, also known as herpes zoster, is a viral infection that causes a painful, blistering rash. While the rash typically heals within a few weeks, some individuals develop chronic nerve pain that lingers for months or even years–a condition known as postherpetic neuralgia (PHN). This persistent nerve pain occurs when the varicella-zoster virus damages nerve fibers, leading to burning, tingling, numbness, and sensitivity long after the rash has disappeared.
At OrthoGen Health, we offer non-surgical regenerative medicine treatments to address shingles-related nerve pain and help restore function. Our team specializes in advanced biologic therapies like platelet-rich plasma (PRP) and exosome therapy, which help reduce inflammation, repair nerve damage, and provide long-term relief.
“Someone referred me to this place because i had a very bad knee pain which multiple other doctors i visited, told me have to have an open surgery but Dr.James told me can do PRP which is much easier and safer. I thought it worth trying it. After almost 2 years, i still have no pain and i got back to normal life. I am so glad listen to Dr, James and for your info i think he has one of the highest certificates that only a few doctors in the US have it.
He is so kind and acknowledgeable and i definitely recommend anyone who has joint pain before letting others to have any open surgeries which obviously they want nothing but making money.Thanks you for making the life enjoyable for me again.”
Symptoms and Causes of Shingles-Related Nerve Pain
Postherpetic neuralgia results from nerve inflammation and scarring caused by the shingles virus. Common symptoms include:
- Persistent burning or stabbing pain in the area where the shingles rash appeared
- Extreme skin sensitivity that makes even light touch painful
- Tingling, numbness, or itching that doesn’t go away
- Pain that intensifies at night or with changes in temperature
PHN is more common in individuals over 50, those with weakened immune systems, or those who experience a severe shingles outbreak.

Non-Surgical Solutions for Postherpetic Neuralgia and Nerve Healing
Traditional treatments for postherpetic neuralgia rely on pain medications, nerve blockers, or antidepressants, which only manage symptoms temporarily. Regenerative medicine offers a natural, long-term solution by promoting nerve healing and reducing inflammation at its source.
Platelet-Rich Plasma (PRP)
Therapy PRP is derived from your own blood and is rich in growth factors that stimulate nerve repair, reduce inflammation, and promote long-term pain relief.
Exosome Therapy
Exosomes are cellular messengers that enhance nerve regeneration and accelerate healing, helping to restore normal nerve function.
Research shows that PRP therapy can significantly reduce nerve pain and improve quality of life for PHN patients, offering an alternative to long-term medication use.
Frequently Asked Questions About Postherpetic Neuralgia Relief
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The varicella-zoster virus damages nerve fibers, leading to lingering pain signals that persist even after the rash heals.
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Yes, these treatments promote nerve regeneration, reduce inflammation, and improve nerve function for lasting relief.
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Absolutely. PRP and exosome therapy are derived from your own body, making them safe and well-tolerated at any age.
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Some patients experience improvements within a few weeks, with continued healing over time.

Dr. James Petros
Dr. James Petros, founder of OrthoGen Health, is a board-certified regenerative medicine physician with extensive expertise in pain management and non-surgical orthopedics. Now serving primarily in his role as CEO, Dr. Petros focuses on advancing the mission of OrthoGen Health through innovation, clinical leadership, and patient-centered strategy. He has built the organization on a foundation of scientific progress, compassionate care, and collaboration, ensuring that patients are supported by a team dedicated to delivering the highest quality regenerative therapies.
Get Non-Surgical Relief for Shingles Pain in San Jose
If you’re struggling with chronic nerve pain after shingles, OrthoGen Health in San Jose and Los Gatos offers regenerative medicine solutions to help restore function and relieve discomfort naturally.
Schedule a consultation today to explore your options for long-term, non-surgical shingles pain relief.