Sciatica, or pinched nerve pain, occurs when the sciatic nerve–the longest nerve in the body–becomes compressed, irritated, or inflamed. This leads to sharp, burning pain that radiates from the lower back down the leg, often accompanied by numbness, tingling, or muscle weakness. Many patients struggle with daily tasks, as walking, sitting, and even sleeping become painful.
At OrthoGen Health, we provide non-surgical regenerative medicine therapies to reduce inflammation, promote nerve healing, and restore function without invasive procedures or long-term medication use. Our advanced treatments harness the body’s natural ability to heal by using biologic materials such as platelet-rich plasma (PRP), stem cells, and exosomes to repair damaged tissue and reduce nerve irritation at the source.
“Someone referred me to this place because i had a very bad knee pain which multiple other doctors i visited, told me have to have an open surgery but Dr.James told me can do PRP which is much easier and safer. I thought it worth trying it. After almost 2 years, i still have no pain and i got back to normal life. I am so glad listen to Dr, James and for your info i think he has one of the highest certificates that only a few doctors in the US have it.
He is so kind and acknowledgeable and i definitely recommend anyone who has joint pain before letting others to have any open surgeries which obviously they want nothing but making money.Thanks you for making the life enjoyable for me again.”
Symptoms and Causes of Sciatica
Sciatica often stems from an underlying spinal condition, such as:
Herniated Discs
When a spinal disc presses on the sciatic nerve
Degenerative Disc Disease
Breakdown of spinal discs leading to nerve compression
Spinal Stenosis
Narrowing of the spinal canal putting pressure on nerves
Piriformis Syndrome
Tightness in the piriformis muscle irritating the sciatic nerve
Sacroiliac (SI) Joint Dysfunction
Inflammation in the SI joint affecting nerve pathways
Symptoms of sciatica can range from mild discomfort to severe, debilitating pain, including:
- Sharp, shooting pain Radiating from the lower back through the buttock and leg
- Burning or tingling sensations Often felt along the nerve pathway
- Muscle weakness Difficulty lifting the foot or maintaining balance
- Increased pain with sitting or standing Changes in posture can worsen symptoms

Non-Surgical Sciatica Treatment in San Jose
Traditional treatments for sciatica often rely on painkillers, steroid injections, or even surgery. However, these approaches only mask symptoms rather than healing the damaged tissue.
At OrthoGen Health, our regenerative medicine therapies help the body repair itself naturally:
Platelet-Rich Plasma (PRP) Therapy
Delivers concentrated growth factors from your own blood to reduce inflammation and promote nerve healing
Stem Cell Therapy
Uses regenerative cells to repair damaged spinal discs and nerve tissue, reducing compression on the sciatic nerve
Exosome Therapy
Enhances communication between cells to accelerate healing and restore nerve function
Research has shown that PRP injections can significantly improve sciatic nerve pain, with many patients experiencing a 50-60% reduction in symptoms over time. Additionally, stem cell therapy has been studied for its potential to regenerate damaged nerve tissue and improve mobility.
Pinched Nerve Treatment Tailored to Your Needs
Each case of sciatica is unique, which is why we create customized treatment plans based on your condition, lifestyle, and recovery goals. Our non-surgical, minimally invasive approach allows patients to heal naturally and avoid prolonged recovery times.

Dr. James Petros
Dr. James Petros, founder of OrthoGen Health, is a board-certified regenerative medicine physician with extensive expertise in pain management and non-surgical orthopedics. Now serving primarily in his role as CEO, Dr. Petros focuses on advancing the mission of OrthoGen Health through innovation, clinical leadership, and patient-centered strategy. He has built the organization on a foundation of scientific progress, compassionate care, and collaboration, ensuring that patients are supported by a team dedicated to delivering the highest quality regenerative therapies.
Find Lasting Sciatica Relief in San Jose and Los Gatos
If you are suffering from sciatic nerve pain, numbness, or weakness, OrthoGen Health in San Jose and Los Gatos offers advanced regenerative medicine solutions to help you regain mobility and live pain-free.
Schedule a consultation today to explore your options for non-surgical sciatica relief.